We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
8
Quercetin shows protective effects
Quercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathways.
We sought to understand how quercetin could alleviate chronic pelvic pain associated with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) using a rat model. Over four weeks, rats received oral quercetin while measuring various blood and prostate health markers.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
Read More
7
Quercetin aids endometrial cell responses
Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis.
We investigated how quercetin, a potential treatment for endometriosis-related pelvic pain, affects endometrial stromal cells. By using cells derived from menstrual effluent of both unaffected individuals and those with endometriosis, we observed quercetin's role in promoting decidualization, which is vital for embryo implantation.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Read More
Most Useful Reviews
9
Eliminated joint pain
10 people found this helpful
Half a year ago, I had Covid, which left me with heavy breathing, shallow shortness of breath, and pain in my bones and joints. After trying various vitamins with little improvement, I started taking quercetin for a month. Now, my shortness of breath has vanished, and my bone and joint pain have significantly reduced. I will continue taking it; it's essential for my health.
Read More
9
Eliminated joint pain
1 people found this helpful
Following my Covid illness six months ago, I struggled with many issues, including joint and bone pain. After a month of using quercetin, I found my breathing improved, and my vitality returned. The joint pain has dramatically lessened, making it a necessity in my first-aid kit.
Read More
7.5
Reduced menstrual pain
15 people found this helpful
To relieve PMS pain, I take a tablet in the morning 30 minutes before meals and add a little vinegar to the water. I combine quercetin with vitamins C, E, and magnesium for support during menstruation. Quercetin is an effective antioxidant that helps prevent estrogen dominance, thus reducing replenishment and pain.
Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies.
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
Read More
9
Quercetin alleviates pelvic pain
Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse.
We explored the effects of Phyllanthus niruri extract and its isolated components, including quercetin, on hemorrhagic cystitis induced by cyclophosphamide in mice. The study involved treatment before and after inducing the condition and assessed pain, swelling, and bleeding.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
Read More
9
Quercetin aids pelvic pain relief
Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT.
We examined the effects of multimodal therapy on chronic pelvic pain using the UPOINT system. After 27 weeks, 100 patients receiving tailored treatments, including quercetin for organ-specific symptoms, showed notable improvement.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
Read More
9
Quercetin shows promise for IC
Treatment of interstitial cystitis with a quercetin supplement.
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
9
Quercetin may reduce pelvic pain
Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial.
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Half a year ago, I had Covid, which left me with heavy breathing, shallow shortness of breath, and pain in my bones and joints. After trying various vitamins with little improvement, I started taking quercetin for a month. Now, my shortness of breath has vanished, and my bone and joint pain have significantly reduced. I will continue taking it; it's essential for my health.
Read More
9
Eliminated joint pain
1 people found this helpful
Following my Covid illness six months ago, I struggled with many issues, including joint and bone pain. After a month of using quercetin, I found my breathing improved, and my vitality returned. The joint pain has dramatically lessened, making it a necessity in my first-aid kit.
Read More
7.5
Reduced menstrual pain
15 people found this helpful
To relieve PMS pain, I take a tablet in the morning 30 minutes before meals and add a little vinegar to the water. I combine quercetin with vitamins C, E, and magnesium for support during menstruation. Quercetin is an effective antioxidant that helps prevent estrogen dominance, thus reducing replenishment and pain.
Read More
7.5
Reduced menstrual pain
6 people found this helpful
I take a tablet in the morning 30 minutes before meals and add some vinegar to the water. Quercetin combined with vitamins C, E, and magnesium provides excellent support during my menstruation. It helps to prevent estrogen dominance and reduces replenishment and pain effectively.
Read More
9
Stomach pain relief
1 people found this helpful
This product is excellent for relieving stomach pain. I experienced sudden discomfort, and after taking one tablet, the pain subsided within half an hour. It also provides anti-inflammatory benefits and general pain relief.
Pelvic pain is a broad term that describes discomfort occurring in the lower abdomen or pelvic region. It can stem from various underlying conditions, involving reproductive organs, the urinary tract, or gastrointestinal issues. Common causes include menstrual cramps, endometriosis, pelvic inflammatory disease, ovarian cysts, and urinary tract infections. Additionally, pelvic pain can be acute, occurring suddenly and sharply, or chronic, lasting for six months or more, significantly impacting one’s quality of life.
Managing pelvic pain often begins with a thorough evaluation from a healthcare provider to determine the underlying causes. Treatment options can vary widely based on the diagnosis and may include medication for pain relief, physical therapy, lifestyle changes, or, in some cases, surgery. Lifestyle adjustments, such as heat therapy and relaxation techniques, can also provide relief. Given the diverse nature of pelvic pain, it’s essential for individuals experiencing persistent discomfort to consult a medical professional for an accurate diagnosis and personalized treatment plan.
Quercetin is a naturally occurring flavonoid that is found in a variety of fruits, vegetables, and grains. Known for its antioxidant properties, quercetin is believed to help combat oxidative stress in the body, which can contribute to various health issues. You can commonly find it in foods such as apples, onions, berries, and citrus fruits, as well as in leafy greens. This makes it a popular dietary supplement among health enthusiasts looking to enhance their overall wellness.
Beyond its antioxidant capacity, quercetin is also being researched for its potential anti-inflammatory effects and benefits for immune support. Some studies suggest that it may help reduce allergy symptoms and improve exercise performance by decreasing muscle fatigue. With its wide range of potential health benefits, quercetin is often marketed as a natural remedy for various ailments, although it’s essential to consult a healthcare professional before starting any new supplement regimen to ensure its safety and effectiveness for your specific needs.
Based on user reviews, many people report seeing improvements in their symptoms within a month of starting quercetin. For instance, one user mentioned that after taking quercetin for a month, their joint pain significantly lessened and their breathing improved following a Covid illness Read Review. Similarly, another review indicated that significant improvements in bone and joint pain were noticed after a month of use Read Review.
In some cases, users have reported more immediate results. One reviewer noted relief from stomach pain within half an hour of taking quercetin Read Review. This suggests that while individual experiences may vary, a period of around 4 weeks seems common for users seeking to relieve pelvic pain and related symptoms.
Quercetin appears to be supported by scientific research as a potential supplement for alleviating pelvic pain, particularly in cases of endometriosis and chronic prostatitis. Several studies indicate that quercetin has anti-inflammatory properties that may contribute to pain relief. For instance, a clinical trial involving women with endometriosis found that a combination treatment including quercetin resulted in a significant reduction in pain associated with conditions like dysmenorrhea and dyspareunia [3]. Additionally, another study noted that quercetin showed promise in reducing pain-related signals in mice with chronic pelvic pain [2].
While these findings are encouraging, the consensus across various research is that further clinical studies are needed to solidify quercetin's effectiveness in human subjects. Some studies suggest it showed a notable reduction in pain and improved quality of life for chronic prostatitis patients [15]. However, not all studies found quercetin to be significantly effective, highlighting the need for personalized treatment approaches [12]. Overall, while quercetin holds potential as a supplement for pelvic pain, its efficacy may vary among individuals, necessitating further investigation to define its therapeutic benefits more clearly.
Based on user reviews, many individuals have reported a variety of symptom improvements after incorporating quercetin into their routines. For instance, users recovering from Covid have highlighted significant reductions in joint pain and breathing difficulties after roughly a month of use. One user shared that after experiencing heavy breathing and bone pain post-Covid, quercetin eliminated their shortness of breath and notably reduced their pain levels Read Review. Another user echoed similar sentiments, noting both improved breathing and a dramatic decrease in joint pain after the same duration Read Review.
In addition to respiratory and joint benefits, users have found quercetin helpful for various forms of discomfort. Some reported rapid relief from stomach pain, with one user stating that their discomfort subsided within thirty minutes of taking the supplement Read Review. Others have also highlighted its effectiveness in alleviating symptoms of nasal congestion and general inflammation, indicating a broad range of potential benefits Read ReviewRead Review. As always, individual experiences may vary, but these testimonials reflect a generally positive outlook on quercetin's impact on various health issues.
Based on user reviews, individuals have experimented with combining quercetin, a supplement known for its antioxidant properties, with other vitamins to manage pelvic pain more effectively. One user reported taking quercetin alongside vitamins C, E, and magnesium to alleviate PMS pain. They suggested that this combination helped to prevent estrogen dominance, subsequently reducing discomfort during menstruation Read Review. Another user echoed similar sentiments, affirming that the combination offers excellent support during menstruation, highlighting the synergistic benefits of quercetin when paired with these vitamins Read Review.
Additionally, users have noted the effectiveness of quercetin for reducing inflammation and general pain, which can be beneficial in managing pelvic discomfort. One user mentioned substantial improvements in pain and overall well-being when combining quercetin with other therapeutic measures during a comprehensive treatment approach for immune boosting and detoxification Read Review. This indicates that users are finding value in integrating various supplements to enhance the effects of quercetin while addressing their pelvic pain symptoms.
Based on user reviews, there seems to be a consensus around the effective dosages and methods for taking quercetin for alleviating pelvic pain and other related issues. A few users noted that taking one tablet in the morning, preferably 30 minutes before meals, can enhance its effectiveness. For instance, one reviewer specifically highlighted combining quercetin with vinegar and supportive vitamins such as C, E, and magnesium to improve its benefits, especially during menstruation Read Review. This combination is said to help prevent estrogen dominance, which may alleviate pain associated with pelvic discomfort Read Review.
On a different note, several users reported noticeable improvements in overall pain management and inflammation reduction after incorporating quercetin into their daily regimen, with some taking it for joint and bone pain specifically following health issues like Covid-19 Read Review. Daily use, typically one capsule, for a few weeks seems to be a common approach without significant side effects reported, making it a trusted choice for those experiencing chronic pain Read Review. Overall, users emphasize that proper dosage and timing appear to enhance quercetin's effectiveness in managing pelvic and joint pain.
9
Eliminated joint pain
1 people found this helpful
Following my Covid illness six months ago, I struggled with many issues, including joint and bone pain. After a month of using quercetin, I found my breathing improved, and my vitality returned. The joint pain has dramatically lessened, making it a necessity in my first-aid kit.
9
Eliminated joint pain
10 people found this helpful
Half a year ago, I had Covid, which left me with heavy breathing, shallow shortness of breath, and pain in my bones and joints. After trying various vitamins with little improvement, I started taking quercetin for a month. Now, my shortness of breath has vanished, and my bone and joint pain have significantly reduced. I will continue taking it; it's essential for my health.
9
Stomach pain relief
1 people found this helpful
This product is excellent for relieving stomach pain. I experienced sudden discomfort, and after taking one tablet, the pain subsided within half an hour. It also provides anti-inflammatory benefits and general pain relief.
9
Reduced inflammation pain
Quercetin is a high-quality product that I've been using as recommended by my doctor for various inflammations and allergic rhinitis. It effectively reduces runny nose symptoms and pain, acting as an efficient antioxidant.
7.5
Relieved joint pain
When used properly, quercetin effectively alleviates nasal congestion, clears mucus from the lungs, and decreases joint pain, assisting in reducing inflammatory processes. It's a high-quality antioxidant with a pleasant taste.
7.5
Reduced menstrual pain
15 people found this helpful
To relieve PMS pain, I take a tablet in the morning 30 minutes before meals and add a little vinegar to the water. I combine quercetin with vitamins C, E, and magnesium for support during menstruation. Quercetin is an effective antioxidant that helps prevent estrogen dominance, thus reducing replenishment and pain.
7.5
Reduced menstrual pain
6 people found this helpful
I take a tablet in the morning 30 minutes before meals and add some vinegar to the water. Quercetin combined with vitamins C, E, and magnesium provides excellent support during my menstruation. It helps to prevent estrogen dominance and reduces replenishment and pain effectively.
7.5
Decreased joint pain
I took this medication with my daughter as part of our comprehensive therapy for immune boosting and detoxification. It has greatly reduced our pain and improved our overall well-being. I highly recommend it!
6
Joint pain relief
2 people found this helpful
I have been taking one capsule of quercetin each day for about two weeks without side effects. It is a remarkable supplement for maintaining the health of blood vessels, increasing their elasticity and strength, while also alleviating joint pain significantly.
9
Quercetin shows promise for endometriosis pain
Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies.
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
7
Ningmitai improves CP/CPPS symptoms
Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity.
We investigated how Ningmitai capsules, which contain quercetin, could help with chronic pelvic pain and inflammation in a specific mouse model.
Our research showed that quercetin can lower pain-related signals and decrease inflammation by affecting immune cell activity.
Overall, treating with Ningmitai resulted in reduced pelvic pain and improved inflammation responses in these mice. Although this study shows promise, the effects may vary in real patients due to the complexity of the condition.
9
Quercetin may reduce pelvic pain
Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial.
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
7
Quercetin's role in pelvic pain
Long-term results of multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome.
We examined the effects of multimodal therapy on chronic prostatitis and chronic pelvic pain, involving 53 patients over a minimum of six months. Our findings showed significant improvements in pain, urinary issues, and quality of life, with 80% of patients reporting better outcomes overall. Notably, 37% of patients used quercetin as part of their treatment. However, while effective for many, not all patients experienced relief, emphasizing the need for tailored approaches to treatment.
References
Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, et al. Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod Biol Endocrinol. 2024;22:100. doi:10.1186/s12958-024-01265-z
Liu H, Wang Z, Xie Q, Chi A, Li Y, et al. Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity. Front Pharmacol. 2022;13:949316. doi:10.3389/fphar.2022.949316
Fadin M, Nicoletti MC, Pellizzato M, Accardi M, Baietti MG, et al. Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies. Minerva Ginecol. 2020;72:285. doi:10.23736/S0026-4784.20.04615-8
Krakhotkin DV, Chernylovskyi VA, Bakurov EE, Sperl J. Evaluation of influence of the UPOINT-guided multimodal therapy in men with chronic prostatitis/chronic pelvic pain syndrome on dynamic values NIH-CPSI: a prospective, controlled, comparative study. Ther Adv Urol. 2019;11:1756287219857271. doi:10.1177/1756287219857271
Maurizi A, De Luca F, Zanghi A, Manzi E, Leonardo C, et al. The role of nutraceutical medications in men with non bacterial chronic prostatitis and chronic pelvic pain syndrome: A prospective non blinded study utilizing flower pollen extracts versus bioflavonoids. Arch Ital Urol Androl. 2019;90:260. doi:10.4081/aiua.2018.4.260
Park S, Lim W, Bazer FW, Whang KY, Song G. Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo. J Nutr Biochem. 2019;63:87. doi:10.1016/j.jnutbio.2018.09.024
Meng LQ, Yang FY, Wang MS, Shi BK, Chen DX, et al. Quercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathways. Prostate. 2018;78:790. doi:10.1002/pros.23536
Schiavi MC, Porpora MG, Vena F, Prata G, Sciuga V, et al. Orally Administered Combination of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin in the Prevention of Postcoital Recurrent Urinary Tract Infections: Analysis of 98 Women in Reproductive Age After 6 Months of Treatment. Female Pelvic Med Reconstr Surg. 2019;25:309. doi:10.1097/SPV.0000000000000560
Güney G, Kaya C, Oto G, Yıldırım S, Özdemir H, et al. Effects of quercetin and surgicel for preventing adhesions after gynecological surgery: A rat uterine horn model. J Obstet Gynaecol Res. 2017;43:179. doi:10.1111/jog.13185
Boeira VT, Leite CE, Santos AA, Edelweiss MI, Calixto JB, et al. Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn Schmiedebergs Arch Pharmacol. 2011;384:265. doi:10.1007/s00210-011-0668-0
Shoskes DA, Nickel JC, Kattan MW. Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT. Urology. 2010;75:1249. doi:10.1016/j.urology.2010.01.021
Shoskes DA, Hakim L, Ghoniem G, Jackson CL. Long-term results of multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome. J Urol. 2003;169:1406.
Shoskes DA, Albakri Q, Thomas K, Cook D. Cytokine polymorphisms in men with chronic prostatitis/chronic pelvic pain syndrome: association with diagnosis and treatment response. J Urol. 2002;168:331.
Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, et al. Treatment of interstitial cystitis with a quercetin supplement. Tech Urol. 2001;7:44.
Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology. 1999;54:960.