Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
USERS' SCORE
Good
Based on 9 Reviews
8.3
Supplement Facts
Serving Size:  1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin C (from ascorbic acid, camu-camu berry extract)
30 mg
33%
Quercetin (as quercetin dihydrate)
250 mg
**
Optimized Food Blend[onion (bulb) (extracts), bitter orange bioflavonoids (peel and fruit), apple (fruit)
220 mg
**
Camu-camu extract (wildcrafted berry)
50 mg
**

Top Medical Research Studies

We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.

The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.

These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
8
Quercetin shows protective effects
We sought to understand how quercetin could alleviate chronic pelvic pain associated with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) using a rat model. Over four weeks, rats received oral quercetin while measuring various blood and prostate health markers.

Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
Read More
We investigated how quercetin, a potential treatment for endometriosis-related pelvic pain, affects endometrial stromal cells. By using cells derived from menstrual effluent of both unaffected individuals and those with endometriosis, we observed quercetin's role in promoting decidualization, which is vital for embryo implantation.

Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Read More

Most Useful Reviews

9
Eliminated joint pain
10 people found this helpful
Half a year ago, I had Covid, which left me with heavy breathing, shallow shortness of breath, and pain in my bones and joints. After trying various vitamins with little improvement, I started taking quercetin for a month. Now, my shortness of breath has vanished, and my bone and joint pain have significantly reduced. I will continue taking it; it's essential for my health.
Read More
9
Eliminated joint pain
1 people found this helpful
Following my Covid illness six months ago, I struggled with many issues, including joint and bone pain. After a month of using quercetin, I found my breathing improved, and my vitality returned. The joint pain has dramatically lessened, making it a necessity in my first-aid kit.
Read More
7.5
Reduced menstrual pain
15 people found this helpful
To relieve PMS pain, I take a tablet in the morning 30 minutes before meals and add a little vinegar to the water. I combine quercetin with vitamins C, E, and magnesium for support during menstruation. Quercetin is an effective antioxidant that helps prevent estrogen dominance, thus reducing replenishment and pain.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
  • All Researches
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.

The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
Read More
We explored the effects of Phyllanthus niruri extract and its isolated components, including quercetin, on hemorrhagic cystitis induced by cyclophosphamide in mice. The study involved treatment before and after inducing the condition and assessed pain, swelling, and bleeding.

We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
Read More
9
Quercetin aids pelvic pain relief
We examined the effects of multimodal therapy on chronic pelvic pain using the UPOINT system. After 27 weeks, 100 patients receiving tailored treatments, including quercetin for organ-specific symptoms, showed notable improvement.

About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
Read More
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.

The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.

These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
9
Quercetin may reduce pelvic pain
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.

Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Eliminated joint pain
10 people found this helpful
Half a year ago, I had Covid, which left me with heavy breathing, shallow shortness of breath, and pain in my bones and joints. After trying various vitamins with little improvement, I started taking quercetin for a month. Now, my shortness of breath has vanished, and my bone and joint pain have significantly reduced. I will continue taking it; it's essential for my health.
Read More
9
Eliminated joint pain
1 people found this helpful
Following my Covid illness six months ago, I struggled with many issues, including joint and bone pain. After a month of using quercetin, I found my breathing improved, and my vitality returned. The joint pain has dramatically lessened, making it a necessity in my first-aid kit.
Read More
7.5
Reduced menstrual pain
15 people found this helpful
To relieve PMS pain, I take a tablet in the morning 30 minutes before meals and add a little vinegar to the water. I combine quercetin with vitamins C, E, and magnesium for support during menstruation. Quercetin is an effective antioxidant that helps prevent estrogen dominance, thus reducing replenishment and pain.
Read More
7.5
Reduced menstrual pain
6 people found this helpful
I take a tablet in the morning 30 minutes before meals and add some vinegar to the water. Quercetin combined with vitamins C, E, and magnesium provides excellent support during my menstruation. It helps to prevent estrogen dominance and reduces replenishment and pain effectively.
Read More
9
Stomach pain relief
1 people found this helpful
This product is excellent for relieving stomach pain. I experienced sudden discomfort, and after taking one tablet, the pain subsided within half an hour. It also provides anti-inflammatory benefits and general pain relief.
Read More

Frequently Asked Questions

9
Eliminated joint pain
1 people found this helpful
Following my Covid illness six months ago, I struggled with many issues, including joint and bone pain. After a month of using quercetin, I found my breathing improved, and my vitality returned. The joint pain has dramatically lessened, making it a necessity in my first-aid kit.
9
Eliminated joint pain
10 people found this helpful
Half a year ago, I had Covid, which left me with heavy breathing, shallow shortness of breath, and pain in my bones and joints. After trying various vitamins with little improvement, I started taking quercetin for a month. Now, my shortness of breath has vanished, and my bone and joint pain have significantly reduced. I will continue taking it; it's essential for my health.
9
Stomach pain relief
1 people found this helpful
This product is excellent for relieving stomach pain. I experienced sudden discomfort, and after taking one tablet, the pain subsided within half an hour. It also provides anti-inflammatory benefits and general pain relief.
9
Reduced inflammation pain
Quercetin is a high-quality product that I've been using as recommended by my doctor for various inflammations and allergic rhinitis. It effectively reduces runny nose symptoms and pain, acting as an efficient antioxidant.
7.5
Relieved joint pain
When used properly, quercetin effectively alleviates nasal congestion, clears mucus from the lungs, and decreases joint pain, assisting in reducing inflammatory processes. It's a high-quality antioxidant with a pleasant taste.
7.5
Reduced menstrual pain
15 people found this helpful
To relieve PMS pain, I take a tablet in the morning 30 minutes before meals and add a little vinegar to the water. I combine quercetin with vitamins C, E, and magnesium for support during menstruation. Quercetin is an effective antioxidant that helps prevent estrogen dominance, thus reducing replenishment and pain.
7.5
Reduced menstrual pain
6 people found this helpful
I take a tablet in the morning 30 minutes before meals and add some vinegar to the water. Quercetin combined with vitamins C, E, and magnesium provides excellent support during my menstruation. It helps to prevent estrogen dominance and reduces replenishment and pain effectively.
7.5
Decreased joint pain
I took this medication with my daughter as part of our comprehensive therapy for immune boosting and detoxification. It has greatly reduced our pain and improved our overall well-being. I highly recommend it!
6
Joint pain relief
2 people found this helpful
I have been taking one capsule of quercetin each day for about two weeks without side effects. It is a remarkable supplement for maintaining the health of blood vessels, increasing their elasticity and strength, while also alleviating joint pain significantly.
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.

The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
7
Ningmitai improves CP/CPPS symptoms
We investigated how Ningmitai capsules, which contain quercetin, could help with chronic pelvic pain and inflammation in a specific mouse model.

Our research showed that quercetin can lower pain-related signals and decrease inflammation by affecting immune cell activity.

Overall, treating with Ningmitai resulted in reduced pelvic pain and improved inflammation responses in these mice. Although this study shows promise, the effects may vary in real patients due to the complexity of the condition.
9
Quercetin may reduce pelvic pain
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.

Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
7
Quercetin's role in pelvic pain
We examined the effects of multimodal therapy on chronic prostatitis and chronic pelvic pain, involving 53 patients over a minimum of six months. Our findings showed significant improvements in pain, urinary issues, and quality of life, with 80% of patients reporting better outcomes overall. Notably, 37% of patients used quercetin as part of their treatment. However, while effective for many, not all patients experienced relief, emphasizing the need for tailored approaches to treatment.

References

  1. Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, et al. Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod Biol Endocrinol. 2024;22:100. doi:10.1186/s12958-024-01265-z
  2. Liu H, Wang Z, Xie Q, Chi A, Li Y, et al. Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity. Front Pharmacol. 2022;13:949316. doi:10.3389/fphar.2022.949316
  3. Fadin M, Nicoletti MC, Pellizzato M, Accardi M, Baietti MG, et al. Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies. Minerva Ginecol. 2020;72:285. doi:10.23736/S0026-4784.20.04615-8
  4. Krakhotkin DV, Chernylovskyi VA, Bakurov EE, Sperl J. Evaluation of influence of the UPOINT-guided multimodal therapy in men with chronic prostatitis/chronic pelvic pain syndrome on dynamic values NIH-CPSI: a prospective, controlled, comparative study. Ther Adv Urol. 2019;11:1756287219857271. doi:10.1177/1756287219857271
  5. Maurizi A, De Luca F, Zanghi A, Manzi E, Leonardo C, et al. The role of nutraceutical medications in men with non bacterial chronic prostatitis and chronic pelvic pain syndrome: A prospective non blinded study utilizing flower pollen extracts versus bioflavonoids. Arch Ital Urol Androl. 2019;90:260. doi:10.4081/aiua.2018.4.260
  6. Park S, Lim W, Bazer FW, Whang KY, Song G. Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo. J Nutr Biochem. 2019;63:87. doi:10.1016/j.jnutbio.2018.09.024
  7. Meng LQ, Yang FY, Wang MS, Shi BK, Chen DX, et al. Quercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathways. Prostate. 2018;78:790. doi:10.1002/pros.23536
  8. Schiavi MC, Porpora MG, Vena F, Prata G, Sciuga V, et al. Orally Administered Combination of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin in the Prevention of Postcoital Recurrent Urinary Tract Infections: Analysis of 98 Women in Reproductive Age After 6 Months of Treatment. Female Pelvic Med Reconstr Surg. 2019;25:309. doi:10.1097/SPV.0000000000000560
  9. Güney G, Kaya C, Oto G, Yıldırım S, Özdemir H, et al. Effects of quercetin and surgicel for preventing adhesions after gynecological surgery: A rat uterine horn model. J Obstet Gynaecol Res. 2017;43:179. doi:10.1111/jog.13185
  10. Boeira VT, Leite CE, Santos AA, Edelweiss MI, Calixto JB, et al. Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn Schmiedebergs Arch Pharmacol. 2011;384:265. doi:10.1007/s00210-011-0668-0
  11. Shoskes DA, Nickel JC, Kattan MW. Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT. Urology. 2010;75:1249. doi:10.1016/j.urology.2010.01.021
  12. Shoskes DA, Hakim L, Ghoniem G, Jackson CL. Long-term results of multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome. J Urol. 2003;169:1406.
  13. Shoskes DA, Albakri Q, Thomas K, Cook D. Cytokine polymorphisms in men with chronic prostatitis/chronic pelvic pain syndrome: association with diagnosis and treatment response. J Urol. 2002;168:331.
  14. Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, et al. Treatment of interstitial cystitis with a quercetin supplement. Tech Urol. 2001;7:44.
  15. Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology. 1999;54:960.
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